If the X-Prize worked to get the private commercial space race kicked off and it was only $10 Million, what would a payout of $1 BILLION do for results. 

This is an ambitious set of problems laid out by the Victory Project. 

To the first person(s) that solves any of these Problems:

1. Develop a cure for breast cancer.
2. Develop a cure for diabetes.
3. Reduce greenhouse emissions from petroleum powered automobiles by 95% without increasing the cost of a normal car more than 5%.
4. Achieve 150 miles per gallon of gasoline in a 3,000 lb. car, using EPA standards; without increasing the cost of a normal car more than 10%.

Is it big?   Yes.

Is it different?   Yes.

Will it work?   Yes.

This is inspiring.  But some of these might take the full Billion dollar prize to develop.

They're looking for donations, feel free to contribute.